人源化肝脏小鼠Hu-URG发表文章（感染乙肝、戊肝、肝细胞移植）：

1. Dicoumarol, an NQO1 inhibitor, blocks cccDNA transcription by promoting degradation of HBx.

2. HAT1 signaling confers to assembly and epigenetic regulation of HBV cccDNA minichromosome.

3. LncRNA PCNAP1 modulates hepatitis B virus replication and enhances tumor growth of liver cancer.

4. A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts.

5. Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions.

6. Human hepatocytes with drug metabolic function induced from fibroblasts by lineage reprogramming.

7. Sphondin efficiently blocks HBsAg production and cccDNA transcription through promoting HBx degradation.

8. DNA Repair Factor Poly(ADP-Ribose) Polymerase 1 Is a Proviral Factor in Hepatitis B Virus Covalently Closed Circular DNA Formation.

9. HBx represses WDR77 to enhance HBV replication by DDB1-mediated WDR77 degradation in the liver.

10. IFN-α inhibits HBV transcription and replication by promoting HDAC3-mediated de-2-hydroxyisobutyrylation of histone H4K8 on HBV cccDNA minichromosome in liver.

11. IFN-α confers epigenetic regulation of HBV cccDNA minichromosome by modulating GCN5-mediated succinylation of histone H3K79 to clear HBV cccDNA.

12. Generation of human hepatocytes from extended pluripotent stem cells.

13. Neuropilin-1 is a novel host factor modulating the entry of hepatitis B virus.

14. A Mouse Model of Inducible Liver Injury Caused by Tet-On Regulated Urokinase for Studies of Hepatocyte Transplantation.

15. Rapid generation of functional hepatocyte-like cells from human adipose-derived stem cells.