Autoimmune disease models

Based on its advanced GEMS platform, we are committed to developing a variety of animal models of autoimmune diseases, covering a wide range of tissue-organ specific and systemic autoimmune diseases. These models simulate the complex pathological processes of human autoimmune diseases through precise gene editing techniques or drug induction methods, and have undergone humanization modifications of important target genes, providing strong support for basic research and drug development.

Strain Name
Model Characteristics

Multiple Sclerosis Models

Muscle stiffness, paralysis, etc.
Autoimmune encephalomyelitis model

Inflammation, demyelination, etc.
Systemic Lupus Erythematosus (SLE) Models

Skin damage, splenomegaly, glomerulonephritis, proteinuria, etc.
Rheumatoid Arthritis Models

Joint inflammation, pain, swelling, etc.
Atopic Dermatitis Models

Itchy skin, etc.
Psoriasis Models

Skin lesions, inflammation, molting, etc.
Inflammatory Bowel Disease Models

Inflammation of the intestinal tract, etc.