B6-hB2M

General Information

Strain Name

B6-B2mem1C(B2M)/Vst

Common Name

B6-hB2M

Source

Beijing Vitalstar Biotechnology Co., Ltd.

Background

C57BL/6N

Fur Color

Black

Edited Gene

B2m (beta-2 microglobulin)

Development

In C57 mice, the mouse B2m gene was replaced with the human B2M gene's coding sequence using CRISPR/Cas9 technology, resulting in the expression of human B2M.

Application Fields of B6-hB2M Mice

1. Immunology research

2. Cancer research

3. Infectious disease research

4. Drug screening


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