General Information
Strain Name | B6-B2mem1C(B2M)/Vst |
Common Name | B6-hB2M |
Source | Beijing Vitalstar Biotechnology Co., Ltd. |
Background | C57BL/6N |
Fur Color | Black |
Edited Gene | B2m (beta-2 microglobulin) |
Development
In C57 mice, the mouse B2m gene was replaced with the human B2M gene's coding sequence using CRISPR/Cas9 technology, resulting in the expression of human B2M.
Application Fields of B6-hB2M Mice
1. Immunology research
2. Cancer research
3. Infectious disease research
4. Drug screening