General Information
Strain Name | B6-Tg (CAG-LSL-C-MYC)/Vst |
Common Name | c-Myc |
Source | Beijing Vitalstar Biotechnology Co., Ltd. |
Background | C57BL/6N |
Fur Color | Black |
Edited Gene | C-MYC (MYC proto-oncogene, bHLH transcription factor) |
Development
The c-Myc (MYC proto-oncogene, bHLH transcription factor) is a proto-oncogene. Overexpression of this gene can lead to the development of tumors.
Mice of this strain need to be paired with appropriate Cre mice. Double-positive mice will develop tumors in the areas where Cre is expressed.
Application Fields for c-Myc Mice
1. Research on liver cancer, lung cancer, gastric cancer, breast cancer, and colon cancer
2. Anti-tumor drug screening