c-Myc

General Information

Strain Name

B6-Tg (CAG-LSL-C-MYC)/Vst

Common Name

c-Myc

Source

Beijing Vitalstar Biotechnology Co., Ltd.

Background

C57BL/6N

Fur Color

Black

Edited Gene

C-MYC (MYC proto-oncogene, bHLH transcription factor)


Development

The c-Myc (MYC proto-oncogene, bHLH transcription factor) is a proto-oncogene. Overexpression of this gene can lead to the development of tumors.

Mice of this strain need to be paired with appropriate Cre mice. Double-positive mice will develop tumors in the areas where Cre is expressed.

Application Fields for c-Myc Mice

1. Research on liver cancer, lung cancer, gastric cancer, breast cancer, and colon cancer

2. Anti-tumor drug screening


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