Dr. Miao Zhenchuan

R&D Director of Beijing VitalStar Biotechnology Co., Ltd. He got Ph.D. from the Institute of Zoology, Chinese Academy of Sciences, and had done research work as postdoctoral fellow on single-cell analysis technology of stem cells at York University in Canada and on hematopoietic stem cell differentiation at the College of Life Sciences, Peking University. He has been engaged in development of humanized animal models for over twenty years. Dr. Miao had been involved in the Global Health Challenge Project funded by the Bill & Melinda Gates Foundation, and leaded his team to successfully create NOD-scid IL2rg^null (NPG) mouse, the first highly immunodeficient mouse strain in China, and establish humanized immune system mouse models based on NPG. Since then, they have developed many next generation NPG mouse strains that have been further modified for being adaptive to various usages. Miao’s team also optimized the protocol for preparing humanized liver mouse models using immunodeficient and inducible liver damage mouse URG and obtained high chimeric rate humanized liver mice. Up to date, they have established tens of thousands of humanized immune system mouse models and humanized liver mouse models for biomedicine research. The series of tumor and liver disease animal models prepared by Dr. Miao and his team have been widely recognized and used in both academia and industry.