Depending on the different objectives of research, different animal models need to be prepared. When studying gene functions, it is necessary to overexpress or knock out the corresponding genes. If the global knockout of the target gene would lead to the death of the animal, or if the gene needs to be knocked out in specific tissues, conditional knockout mice or rats can be prepared. To establish a gene mutation model, point mutation animal models are prepared. When preparing humanized mice or rats for genes, replacement with human genes can be carried out. To prepare different animal models, corresponding strategies must be adopted to successfully obtain the target models.
Types of Gene Editing
Vitalstar has established a system for preparing various types of genetically edited animals. We can design process according to your experimental requirements and use the appropriate editing types to accurately and efficiently prepare target animal models, such as:
· Global Knockout
· Conditional Knockout
· Random Transgenesis
· "safe harbor" locus Knock-in
· Gene Knock-in
· Gene Replacement
· Point Mutation